Cargando…
Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Biochemistry and Molecular Biology, Inc. Published by Elsevier Inc.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100306/ http://dx.doi.org/10.1016/j.jbc.2023.103683 |
| _version_ | 1785025248326844416 |
|---|---|
| author | Dumm, Adaira Sommers, Joshua Loftus, Lorin Jones, Martin Lee, Rebecca Haren, Caitlin Brosh, Robert |
| author_facet | Dumm, Adaira Sommers, Joshua Loftus, Lorin Jones, Martin Lee, Rebecca Haren, Caitlin Brosh, Robert |
| author_sort | Dumm, Adaira |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-10100306 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | The American Society for Biochemistry and Molecular Biology, Inc. Published by Elsevier Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-101003062023-04-13 Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc Dumm, Adaira Sommers, Joshua Loftus, Lorin Jones, Martin Lee, Rebecca Haren, Caitlin Brosh, Robert J Biol Chem Topic Category Chemical Biology, Drug Discovery and Bioanalytical Methods The American Society for Biochemistry and Molecular Biology, Inc. Published by Elsevier Inc. 2023 2023-04-13 /pmc/articles/PMC10100306/ http://dx.doi.org/10.1016/j.jbc.2023.103683 Text en Copyright © 2023 The American Society for Biochemistry and Molecular Biology, Inc. Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Topic Category Chemical Biology, Drug Discovery and Bioanalytical Methods Dumm, Adaira Sommers, Joshua Loftus, Lorin Jones, Martin Lee, Rebecca Haren, Caitlin Brosh, Robert Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title | Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title_full | Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title_fullStr | Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title_full_unstemmed | Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title_short | Abstract 2677: The SARS-CoV-2 Nsp13 Helicase Required for Coronavirus Replication Interacts with Structured Nucleic Acids in a Strand-Specific Manner and Catalyzes a Novel Protein-RNA Remodeling Activity Implicated in the Proofreading Mechanism of the Replication-Transc |
| title_sort | abstract 2677: the sars-cov-2 nsp13 helicase required for coronavirus replication interacts with structured nucleic acids in a strand-specific manner and catalyzes a novel protein-rna remodeling activity implicated in the proofreading mechanism of the replication-transc |
| topic | Topic Category Chemical Biology, Drug Discovery and Bioanalytical Methods |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100306/ http://dx.doi.org/10.1016/j.jbc.2023.103683 |
| work_keys_str_mv | AT dummadaira abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT sommersjoshua abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT loftuslorin abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT jonesmartin abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT leerebecca abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT harencaitlin abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc AT broshrobert abstract2677thesarscov2nsp13helicaserequiredforcoronavirusreplicationinteractswithstructurednucleicacidsinastrandspecificmannerandcatalyzesanovelproteinrnaremodelingactivityimplicatedintheproofreadingmechanismofthereplicationtransc |