Cargando…

Atorvastatin Potentially Reduces Mycobacterial Severity through Its Action on Lipoarabinomannan and Drug Permeability in Granulomas

The majority of preclinical research has shown that Mycobacterium tuberculosis can modify host lipids in various ways. To boost its intramacrophage survival, M. tuberculosis causes host lipids to build up, resulting in the development of lipid-laden foam cells. M. tuberculosis binds to and enters th...

Descripción completa

Detalles Bibliográficos
Autores principales: Davuluri, Kusuma Sai, Singh, Amit Kumar, Singh, Ajay Vir, Chaudhary, Pooja, Raman, Sunil Kumar, Kushwaha, Shweta, Singh, Shoor Vir, Chauhan, Devendra Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100658/
https://www.ncbi.nlm.nih.gov/pubmed/36719189
http://dx.doi.org/10.1128/spectrum.03197-22