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Conserved Expression and Functionality of Furin between Chickens and Ducks as an Activating Protease of Highly Pathogenic Avian Influenza Virus Hemagglutinins

Highly pathogenic avian influenza viruses (HPAIVs) typically emerge from low-pathogenic avian influenza viruses (LPAIVs) of the H5 and H7 subtypes upon spillover from wild aquatic birds into poultry. The conversion from LPAIV to HPAIV is characterized by the acquisition of a multibasic cleavage site...

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Detalles Bibliográficos
Autores principales:	de Bruin, Anja C. M., Spronken, Monique I., Bestebroer, Theo M., Fouchier, Ron A. M., Richard, Mathilde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100678/ https://www.ncbi.nlm.nih.gov/pubmed/36916982 http://dx.doi.org/10.1128/spectrum.04602-22

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