Validation of a Reporter Cell Line for Flavivirus Inhibition Assays

Here, we report the validation of a new reporter cell line, Hec1a-IFNB-Luc, for use in inhibition studies of various flaviviruses relevant to human pathology. The reporter system allows the detection of viral replication after luciferase gene activation driven by an interferon beta (IFN-β) promoter....

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Detalles Bibliográficos
Autores principales: Rezende, Tatiana M. T., Macera, Gabriella, Heyndrickx, Leo, Michiels, Johan, Coppens, Sandra, Thibaut, Hendrik Jan, Dallmeier, Kai, Van Esbroeck, Marjan, Neyts, Johan, Ariën, Kevin K., Bartholomeeusen, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Methods and Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100686/
https://www.ncbi.nlm.nih.gov/pubmed/36786659
http://dx.doi.org/10.1128/spectrum.05027-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100686/
https://www.ncbi.nlm.nih.gov/pubmed/36786659
http://dx.doi.org/10.1128/spectrum.05027-22

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