Murine Gammaherpesvirus 68 ORF45 Stimulates B2 Retrotransposon and Pre-tRNA Activation in a Manner Dependent on Mitogen-Activated Protein Kinase (MAPK) Signaling

RNA polymerase III (RNAPIII) transcribes a variety of noncoding RNAs, including tRNA (tRNA) and the B2 family of short interspersed nuclear elements (SINEs). B2 SINEs are noncoding retrotransposons that possess tRNA-like promoters and are normally silenced in healthy somatic tissue. Infection with t...

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Detalles Bibliográficos
Autores principales: Lari, Azra, Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100704/
https://www.ncbi.nlm.nih.gov/pubmed/36752632
http://dx.doi.org/10.1128/spectrum.00172-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100704/
https://www.ncbi.nlm.nih.gov/pubmed/36752632
http://dx.doi.org/10.1128/spectrum.00172-23

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