Cargando…

Expression of Human Endogenous Retrovirus Group K (HERV-K) HML-2 Correlates with Immune Activation of Macrophages and Type I Interferon Response

Human endogenous retroviruses (HERVs) comprise about 8.3% of the human genome and are capable of producing RNA molecules that can be sensed by pattern recognition receptors, leading to the activation of innate immune response pathways. The HERV-K (HML-2) subgroup is the youngest HERV clade with the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Russ, Eric, Mikhalkevich, Natallia, Iordanskiy, Sergey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100713/ https://www.ncbi.nlm.nih.gov/pubmed/36861980 http://dx.doi.org/10.1128/spectrum.04438-22

Ejemplares similares

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma
por: Schmitt, Katja, et al.
Publicado: (2013)

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
por: Subramanian, Ravi P, et al.
Publicado: (2011)

Preferential expression of human endogenous retrovirus K (HERV-K/HML-2) type 1 in tumor cells
por: Romano, Camila M, et al.
Publicado: (2011)

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project
por: Flockerzi, Aline, et al.
Publicado: (2008)

HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease
por: Hohn, Oliver, et al.
Publicado: (2013)

Human Endogenous Retrovirus K (HML-2) in Health and Disease
por: Xue, Bei, et al.
Publicado: (2020)

Ancient Adversary – HERV-K (HML-2) in Cancer
por: Dervan, Eoin, et al.
Publicado: (2021)

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec
por: Ruggieri, Alessia, et al.
Publicado: (2009)

Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
por: Jia, Lei, et al.
Publicado: (2022)

Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses
por: Mikhalkevich, Natallia, et al.
Publicado: (2021)

A Comprehensive Analysis of Human Endogenous Retroviruses HERV-K (HML.2) from Teratocarcinoma Cell Lines and Detection of Viral Cargo in Microvesicles
por: Morozov, Vladimir A., et al.
Publicado: (2021)

Human endogenous retroviruses of the HERV-K (HML-2) family are expressed in the brain of healthy individuals and modify the composition of the brain-infiltrating immune cells
por: Nevalainen, Tapio, et al.
Publicado: (2023)

High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients
por: Guo, Yaolin, et al.
Publicado: (2022)

Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Human Endogenous Retroviruses-K (HML-2) Expression Is Correlated with Prognosis and Progress of Hepatocellular Carcinoma
por: Ma, Weijie, et al.
Publicado: (2016)

Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
por: Chudak, Claudia, et al.
Publicado: (2013)

Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
por: Chudak, Claudia, et al.
Publicado: (2013)

Correction to: Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Endogenous Retroviruses as Modulators of Innate Immunity
por: Russ, Eric, et al.
Publicado: (2023)

Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
por: Burn, Aidan, et al.
Publicado: (2022)

Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients
por: Shah, Ashish H., et al.
Publicado: (2022)

Expression profiles of human endogenous retrovirus (HERV)-K and HERV-R Env proteins in various cancers
por: Ko, Eun-Ji, et al.
Publicado: (2021)

Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
por: Kang, Qian, et al.
Publicado: (2023)

Exploring HERV-K (HML-2) Influence in Cancer and Prospects for Therapeutic Interventions
por: Costa, Bárbara, et al.
Publicado: (2023)

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
por: Mayer, Jens, et al.
Publicado: (2018)

Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi’s Sarcoma development
por: Dai, Lu, et al.
Publicado: (2018)

Expression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors
por: Kessler, Almuth Friederike, et al.
Publicado: (2014)

Is the HERV-K HML-2 Xq21.33, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?
por: Kaplan, Mark H., et al.
Publicado: (2020)

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers
por: de Mulder, Miguel, et al.
Publicado: (2017)

Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2022)

Insertionally polymorphic sites of human endogenous retrovirus-K (HML-2) with long target site duplications
por: Kahyo, Tomoaki, et al.
Publicado: (2017)

Identification of the distribution of human endogenous retroviruses K (HML-2) by PCR-based target enrichment sequencing
por: Xue, Bei, et al.
Publicado: (2020)

Evidence for replication of human endogenous retroviruses type-K (HERV-K) in HIV-1 positive patients
por: Contreras-Galindo, Rafael, et al.
Publicado: (2006)

The Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression
por: Morozov, Vladimir A., et al.
Publicado: (2013)

Detection of Human Endogenous Retrovirus K (HERV-K) Transcripts in Human Prostate Cancer Cell Lines
por: Agoni, Lorenzo, et al.
Publicado: (2013)

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
por: Broecker, Felix, et al.
Publicado: (2016)

Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
por: Scognamiglio, Sante, et al.
Publicado: (2022)

Human Endogenous Retrovirus K106 (HERV-K106) Was Infectious after the Emergence of Anatomically Modern Humans
por: Jha, Aashish R., et al.
Publicado: (2011)

Human endogenous retrovirus K (HERV-K) transcripts detection in babies exposed to HIV-1 during pregnancy
por: Romano, Camila M, et al.
Publicado: (2014)

Human Endogenous Retrovirus K (HERV-K) can drive gene expression as a promoter in Caenorhabditis elegans
por: Durnaoglu, Serpen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ipbjpqbam5itutr89k972qv4hj