Virtual Screening and In Vitro Experimental Verification of LuxS Inhibitors for Escherichia coli O157:H7

Enterohemorrhagic Escherichia coli O157:H7 is an important foodborne pathogen that forms biofilms. In this study, three quorum-sensing (QS) inhibitors (M414-3326, 3254-3286, and L413-0180) were obtained through virtual screening, and their in vitro antibiofilm activities were validated. Briefly, the...

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Detalles Bibliográficos
Autores principales: Bai, Yu-Bin, Yang, Xiao-Rong, Li, Bing, Zhou, Xu-Zheng, Wang, Wei-Wei, Cheng, Fu-Sheng, Zhang, Ji-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100900/
https://www.ncbi.nlm.nih.gov/pubmed/36809060
http://dx.doi.org/10.1128/spectrum.03502-22

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