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Coimmunization with Preerythrocytic Antigens alongside Circumsporozoite Protein Can Enhance Sterile Protection against Plasmodium Sporozoite Infection

Malaria-causing Plasmodium parasites have a complex life cycle and present numerous antigen targets that may contribute to protective immune responses. The currently recommended vaccine—RTS,S—functions by targeting the Plasmodium falciparum circumsporozoite protein (CSP), which is the most abundant...

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Detalles Bibliográficos
Autores principales:	Vigdorovich, Vladimir, Patel, Hardik, Watson, Alexander, Raappana, Andrew, Reynolds, Laura, Selman, William, Beeman, Suzannah, Edlefsen, Paul T., Kappe, Stefan H. I., Sather, D. Noah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100930/ https://www.ncbi.nlm.nih.gov/pubmed/36847573 http://dx.doi.org/10.1128/spectrum.03791-22

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