High-Throughput Mutagenesis Reveals a Role for Antimicrobial Resistance- and Virulence-Associated Mobile Genetic Elements in Staphylococcus aureus Host Adaptation

Methicillin-resistant Staphylococcus aureus (MRSA) clonal-complex 398 (CC398) is the dominant livestock-associated (LA) MRSA lineage in European livestock and an increasing cause of difficult-to-treat human disease. LA-CC398 MRSA evolved from a diverse human-associated methicillin-sensitive populati...

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Detalles Bibliográficos
Autores principales: Ba, Xiaoliang, Matuszewska, Marta, Kalmar, Lajos, Fan, Jingyan, Zou, Geng, Corander, Desirée, Raisen, Claire L., Li, Shaowen, Li, Lu, Weinert, Lucy A., Tucker, Alexander W., Grant, Andrew J., Zhou, Rui, Holmes, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101091/
https://www.ncbi.nlm.nih.gov/pubmed/36815781
http://dx.doi.org/10.1128/spectrum.04213-22

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