Engineered Bacteria for Short-Chain-Fatty-Acid-Repressed Expression of Biotherapeutic Molecules

Short-chain fatty acids (SCFA) such as propionate and butyrate are critical metabolites produced by the gut microbiota. Microbiome dysbiosis resulting in altered SCFA profiles is associated with certain diseases, including inflammatory bowel diseases (IBD), characterized by a reduction in butyrate c...

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Detalles Bibliográficos
Autores principales: Serebrinsky-Duek, Kineret, Barra, Maria, Danino, Tal, Garrido, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101121/
https://www.ncbi.nlm.nih.gov/pubmed/36939337
http://dx.doi.org/10.1128/spectrum.00049-23

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