Arthrocolins Synergizing with Fluconazole Inhibit Fluconazole-Resistant Candida albicans by Increasing Riboflavin Metabolism and Causing Mitochondrial Dysfunction and Autophagy

Our previous study reported that seminaturally occurring arthrocolins A to C with unprecedented carbon skeletons could restore the antifungal activity of fluconazole against fluconazole-resistant Candida albicans. Here, we showed that arthrocolins synergized with fluconazole, reducing the fluconazol...

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Detalles Bibliográficos
Autores principales: Wu, Zhuang, Wu, Qun-Fu, Yuan, Wen-Li, Chen, Yong-Hong, Hu, Di, Deng, De-Yao, Zhang, Long-Long, Niu, Xue-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101122/
https://www.ncbi.nlm.nih.gov/pubmed/36847492
http://dx.doi.org/10.1128/spectrum.04051-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101122/
https://www.ncbi.nlm.nih.gov/pubmed/36847492
http://dx.doi.org/10.1128/spectrum.04051-22

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