Heterocyclic Diaryliodonium-Based Inhibitors of Carbapenem-Resistant Acinetobacter baumannii

Finding new therapeutic strategies against Gram-negative pathogens such as Acinetobacter baumannii is challenging. Starting from diphenyleneiodonium (dPI) salts, which are moderate Gram-positive antibacterials, we synthesized a focused heterocyclic library and found a potent inhibitor of patient-der...

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Detalles Bibliográficos
Autores principales: Kumari, Pooja, Kaul, Grace, Kumar, T. Anand, Akhir, Abdul, Shukla, Manjulika, Sharma, Suraj, Kamat, Siddhesh S., Chopra, Sidharth, Chakrapani, Harinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101131/
https://www.ncbi.nlm.nih.gov/pubmed/36976008
http://dx.doi.org/10.1128/spectrum.04773-22

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