Cargando…

L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum

OBJECTIVE: Vascular endothelial growth factor (VEGF) plays a key role in diabetic retinopathy (DR). Previously, we have reported an association between mutations in a gene coding for the L-type calcium channel subunit, VEGF and DR. L-type calcium channel blockers (LTCCBs) have been widely used as an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Anmol, Mutter, Stefan, Parente, Erika B., Harjutsalo, Valma, Lithovius, Raija, Mathavan, Sinnakaruppan, Lehto, Markku, Hiltunen, Timo P., Kontula, Kimmo K., Groop, Per-Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101440/ https://www.ncbi.nlm.nih.gov/pubmed/37053203 http://dx.doi.org/10.1371/journal.pone.0284364

Ejemplares similares

Medication profiling in women with type 1 diabetes highlights the importance of adequate, guideline-based treatment in low-risk groups
por: Lithovius, Raija, et al.
Publicado: (2023)

Relationship between ABO blood groups and cardiovascular disease in type 1 diabetes according to diabetic nephropathy status
por: Parente, Erika B., et al.
Publicado: (2020)

Waist-height ratio and waist are the best estimators of visceral fat in type 1 diabetes
por: Parente, Erika B., et al.
Publicado: (2020)

The impact of central obesity on the risk of hospitalization or death due to heart failure in type 1 diabetes: a 16-year cohort study
por: Parente, Erika B., et al.
Publicado: (2021)

Waist-Height Ratio and the Risk of Severe Diabetic Eye Disease in Type 1 Diabetes: A 15-Year Cohort Study
por: Parente, Erika B, et al.
Publicado: (2021)

Endotoxins are associated with visceral fat mass in type 1 diabetes
por: Lassenius, Mariann I., et al.
Publicado: (2016)

Dietary patterns reflecting healthy food choices are associated with lower serum LPS activity
por: Ahola, Aila J, et al.
Publicado: (2017)

Meal timing, meal frequency, and breakfast skipping in adult individuals with type 1 diabetes – associations with glycaemic control
por: Ahola, Aila J., et al.
Publicado: (2019)

Bacterial infections in patients with type 1 diabetes: a 14-year follow-up study
por: Simonsen, Johan R, et al.
Publicado: (2015)

Bacterial infections as novel risk factors of severe diabetic retinopathy in individuals with type 1 diabetes
por: Simonsen, Johan Rasmus, et al.
Publicado: (2021)

Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort study
por: Harjutsalo, Valma, et al.
Publicado: (2011)

Exercise and nutrition in type 1 diabetes: Insights from the FinnDiane cohort
por: Pongrac Barlovic, Drazenka, et al.
Publicado: (2022)

Age at Onset of Type 1 Diabetes in Parents and Recurrence Risk in Offspring
por: Harjutsalo, Valma, et al.
Publicado: (2010)

The impact of diabetic nephropathy and severe diabetic retinopathy on chronic limb threatening ischemia risk in individuals with type 1 diabetes: a nationwide, population study
por: Harjutsalo, Valma, et al.
Publicado: (2023)

Perceived Stress and Adherence to the Dietary Recommendations and Blood Glucose Levels in Type 1 Diabetes
por: Ahola, Aila J., et al.
Publicado: (2020)

Age at Onset and the Risk of Proliferative Retinopathy in Type 1 Diabetes
por: Hietala, Kustaa, et al.
Publicado: (2010)

Nut Consumption Is Associated with Lower Risk of Metabolic Syndrome and Its Components in Type 1 Diabetes
por: Ahola, Aila J., et al.
Publicado: (2021)

Rate of Kidney Function Decline is Associated With Kidney and Heart Failure in Individuals With Type 1 Diabetes
por: Sandholm, Niina, et al.
Publicado: (2023)

Sphingomyelin and progression of renal and coronary heart disease in individuals with type 1 diabetes
por: Pongrac Barlovic, Drazenka, et al.
Publicado: (2020)

Higher HbA(1c) variability is associated with increased arterial stiffness in individuals with type 1 diabetes
por: Tynjälä, Anniina, et al.
Publicado: (2023)

Correction: Higher HbA(1c) variability is associated with increased arterial stiffness in individuals with type 1 diabetes
por: Tynjälä, Anniina, et al.
Publicado: (2023)

Symptoms of depression are associated with reduced leisure-time physical activity in adult individuals with type 1 diabetes
por: Ahola, Aila J., et al.
Publicado: (2021)

Dietary intake and hospitalisation due to diabetic ketoacidosis and hypoglycaemia in individuals with type 1 diabetes
por: Ahola, Aila J., et al.
Publicado: (2021)

Pulse Pressure Predicts Incident Cardiovascular Disease but Not Diabetic Nephropathy in Patients With Type 1 Diabetes (The FinnDiane Study)
por: Gordin, Daniel, et al.
Publicado: (2011)

Osteoprotegerin Is an Independent Predictor of Vascular Events in Finnish Adults With Type 1 Diabetes
por: Gordin, Daniel, et al.
Publicado: (2013)

Decline in the Cumulative Incidence of Severe Diabetic Retinopathy in Patients With Type 1 Diabetes
por: Kytö, Janne P., et al.
Publicado: (2011)

The Gut-Kidney Axis: Putative Interconnections Between Gastrointestinal and Renal Disorders
por: Lehto, Markku, et al.
Publicado: (2018)

Genetic factors affect the susceptibility to bacterial infections in diabetes
por: Simonsen, Johan R., et al.
Publicado: (2021)

Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes
por: Sandholm, Niina, et al.
Publicado: (2018)

Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease
por: Smidtslund, Patrik, et al.
Publicado: (2023)

The Association Between Dietary Sodium Intake, ESRD, and All-Cause Mortality in Patients With Type 1 Diabetes
por: Thomas, Merlin C., et al.
Publicado: (2011)

Frequent physical activity is associated with reduced risk of severe diabetic retinopathy in type 1 diabetes
por: Tikkanen-Dolenc, Heidi, et al.
Publicado: (2019)

Insulin exposure mitigates the increase of arterial stiffness in patients with type 2 diabetes and albuminuria: an exploratory analysis
por: Gordin, Daniel, et al.
Publicado: (2019)

The impact of parental risk factors on the risk of stroke in type 1 diabetes
por: Ylinen, Anni, et al.
Publicado: (2021)

Incidence of Stroke According to Presence of Diabetic Nephropathy and Severe Diabetic Retinopathy in Patients With Type 1 Diabetes
por: Hägg, Stefanie, et al.
Publicado: (2013)

Apolipoprotein C‐III predicts cardiovascular events and mortality in individuals with type 1 diabetes and albuminuria
por: Jansson Sigfrids, Fanny, et al.
Publicado: (2021)

Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension
por: Hiltunen, Timo P., et al.
Publicado: (2017)

Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study
por: Sánez Tähtisalo, Heini, et al.
Publicado: (2020)

Subarachnoid Hemorrhage in Type 1 Diabetes: A prospective cohort study of 4,083 patients with diabetes
por: Korja, Miikka, et al.
Publicado: (2013)

The role of blood pressure in risk of ischemic and hemorrhagic stroke in type 1 diabetes
por: Hägg-Holmberg, Stefanie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cbi3dnqbj66uantq8foc18gu23