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Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries
This study compared the postoperative analgesic efficacy of intraperitoneal and incisional lidocaine versus ropivacaine in dogs undergoing major abdominal surgeries. Dogs randomly received intraperitoneal lidocaine irrigation (4 mg kg(-1), diluted to 5 ml kg(-1), L group), ropivacaine (4 mg kg(-1),...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101502/ https://www.ncbi.nlm.nih.gov/pubmed/37053210 http://dx.doi.org/10.1371/journal.pone.0284379 |
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author | Brioschi, Federica Alessandra Ravasio, Giuliano Ferrari, Francesco Amari, Martina Di Cesare, Federica Valentini Visentin, Martina Rabbogliatti, Vanessa |
author_facet | Brioschi, Federica Alessandra Ravasio, Giuliano Ferrari, Francesco Amari, Martina Di Cesare, Federica Valentini Visentin, Martina Rabbogliatti, Vanessa |
author_sort | Brioschi, Federica Alessandra |
collection | PubMed |
description | This study compared the postoperative analgesic efficacy of intraperitoneal and incisional lidocaine versus ropivacaine in dogs undergoing major abdominal surgeries. Dogs randomly received intraperitoneal lidocaine irrigation (4 mg kg(-1), diluted to 5 ml kg(-1), L group), ropivacaine (4 mg kg(-1), diluted to 5 ml kg(-1), R group) or 0.9% saline (5 ml kg(-1), C group). Prior to skin closure, dogs received incisional lidocaine 2 mg kg(-1) (group L), incisional ropivacaine 2 mg kg(-1) (group R) or incisional saline 0.2 ml kg(-1) (group C). Pain was assessed at different time points up to 24 hours after extubation, using the Short Form-Glasgow Composite Measure Pain Scale and VAS Scale. In group C, postoperative pain scores were significantly higher than in groups L and R from T0.5 to T6 (p < 0.05). In R group, postoperative pain scores were significantly lower than in groups L and C from T12 to T24 (p < 0.05). Rescue analgesia was administered to 5/11 dogs in L group, 1/10 dogs in R group and 8/10 dogs in C group. Groups L and R experienced a significantly lower postoperative pain during the first 6 hours after extubation, compared with group C. Ropivacaine provided lower postoperative pain scores than lidocaine and saline up to 24 hours after extubation. According to the obtained results, ropivacaine seemed to provide better and longer lasting postoperative analgesia compared with lidocaine. Therefore, intraperitoneal and incisional administration of ropivacaine in dogs undergoing major abdominal surgeries is recommended. |
format | Online Article Text |
id | pubmed-10101502 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-101015022023-04-14 Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries Brioschi, Federica Alessandra Ravasio, Giuliano Ferrari, Francesco Amari, Martina Di Cesare, Federica Valentini Visentin, Martina Rabbogliatti, Vanessa PLoS One Research Article This study compared the postoperative analgesic efficacy of intraperitoneal and incisional lidocaine versus ropivacaine in dogs undergoing major abdominal surgeries. Dogs randomly received intraperitoneal lidocaine irrigation (4 mg kg(-1), diluted to 5 ml kg(-1), L group), ropivacaine (4 mg kg(-1), diluted to 5 ml kg(-1), R group) or 0.9% saline (5 ml kg(-1), C group). Prior to skin closure, dogs received incisional lidocaine 2 mg kg(-1) (group L), incisional ropivacaine 2 mg kg(-1) (group R) or incisional saline 0.2 ml kg(-1) (group C). Pain was assessed at different time points up to 24 hours after extubation, using the Short Form-Glasgow Composite Measure Pain Scale and VAS Scale. In group C, postoperative pain scores were significantly higher than in groups L and R from T0.5 to T6 (p < 0.05). In R group, postoperative pain scores were significantly lower than in groups L and C from T12 to T24 (p < 0.05). Rescue analgesia was administered to 5/11 dogs in L group, 1/10 dogs in R group and 8/10 dogs in C group. Groups L and R experienced a significantly lower postoperative pain during the first 6 hours after extubation, compared with group C. Ropivacaine provided lower postoperative pain scores than lidocaine and saline up to 24 hours after extubation. According to the obtained results, ropivacaine seemed to provide better and longer lasting postoperative analgesia compared with lidocaine. Therefore, intraperitoneal and incisional administration of ropivacaine in dogs undergoing major abdominal surgeries is recommended. Public Library of Science 2023-04-13 /pmc/articles/PMC10101502/ /pubmed/37053210 http://dx.doi.org/10.1371/journal.pone.0284379 Text en © 2023 Brioschi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Brioschi, Federica Alessandra Ravasio, Giuliano Ferrari, Francesco Amari, Martina Di Cesare, Federica Valentini Visentin, Martina Rabbogliatti, Vanessa Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title | Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title_full | Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title_fullStr | Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title_full_unstemmed | Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title_short | Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
title_sort | comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101502/ https://www.ncbi.nlm.nih.gov/pubmed/37053210 http://dx.doi.org/10.1371/journal.pone.0284379 |
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