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Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study

The global incidence of infertility is increasing year by year, and the association between infertility and mental illness has been widely concerned. The aim of this study was to investigate the incidence of anxiety and depression in infertile women in China and explore the risk factors which might...

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Autores principales: Wang, Lingyan, Tang, Youyin, Wang, Yuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101516/
https://www.ncbi.nlm.nih.gov/pubmed/37053254
http://dx.doi.org/10.1371/journal.pone.0284414
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author Wang, Lingyan
Tang, Youyin
Wang, Yuyang
author_facet Wang, Lingyan
Tang, Youyin
Wang, Yuyang
author_sort Wang, Lingyan
collection PubMed
description The global incidence of infertility is increasing year by year, and the association between infertility and mental illness has been widely concerned. The aim of this study was to investigate the incidence of anxiety and depression in infertile women in China and explore the risk factors which might lead to anxiety and depression. From January 2020 to December 2020, female infertile patients who received assisted reproduction technology (ART) treatment at West China Second Hospital were recruited and a total of 1712 eligible female patients were finally enrolled in this study. Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionaire-9 (PHQ-9) were used to evaluate the patients’ psychological status. The reliability of all scales was evaluated by Cronbach’s α and Spearman-Brown half coefficient, and Kaiser-Meyer-Olkin (KMO) value was calculated by factor analysis to evaluate validity. Univariate and multivariate logistic regression analysis were applied for assessing independent risk factors of anxiety and depression, respectively. The incidence of anxiety and depression in infertile women were 25.2% and 31.3%, respectively. Cronbach’s α coefficients and Spearman-Brown half-fold coefficients of GAD-7 and PHQ-9 were 0.870, 0.825, 0.852 and 0.793, respectively. Univariate and multivariate logistic regression analysis showed that education level (junior college degree or above, OR:1. 6, 95% CI: 1.2–2.1, P = 0.003), somatic symptoms (severe somatic symptoms, OR:15.2, 95%CI: 5.6–41.3, P<0.001), sleep quality (poor sleep quality, OR:9.3, 95% CI:4.7–18.4, P<0.001) were independent risk factors for anxiety. And age>35 years old, moderate and severe somatic symptoms and poor sleep quality were independent risk factors for depression. Somatic symptoms and poor sleep quality are both the risk factors of anxiety and depression symptoms of infertile woman. And high educated (junior college degree or above) patients are more likely to be complicated with anxiety symptoms, while elderly patients (age>35) are prone to be complicated with depression symptoms.
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spelling pubmed-101015162023-04-14 Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study Wang, Lingyan Tang, Youyin Wang, Yuyang PLoS One Research Article The global incidence of infertility is increasing year by year, and the association between infertility and mental illness has been widely concerned. The aim of this study was to investigate the incidence of anxiety and depression in infertile women in China and explore the risk factors which might lead to anxiety and depression. From January 2020 to December 2020, female infertile patients who received assisted reproduction technology (ART) treatment at West China Second Hospital were recruited and a total of 1712 eligible female patients were finally enrolled in this study. Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionaire-9 (PHQ-9) were used to evaluate the patients’ psychological status. The reliability of all scales was evaluated by Cronbach’s α and Spearman-Brown half coefficient, and Kaiser-Meyer-Olkin (KMO) value was calculated by factor analysis to evaluate validity. Univariate and multivariate logistic regression analysis were applied for assessing independent risk factors of anxiety and depression, respectively. The incidence of anxiety and depression in infertile women were 25.2% and 31.3%, respectively. Cronbach’s α coefficients and Spearman-Brown half-fold coefficients of GAD-7 and PHQ-9 were 0.870, 0.825, 0.852 and 0.793, respectively. Univariate and multivariate logistic regression analysis showed that education level (junior college degree or above, OR:1. 6, 95% CI: 1.2–2.1, P = 0.003), somatic symptoms (severe somatic symptoms, OR:15.2, 95%CI: 5.6–41.3, P<0.001), sleep quality (poor sleep quality, OR:9.3, 95% CI:4.7–18.4, P<0.001) were independent risk factors for anxiety. And age>35 years old, moderate and severe somatic symptoms and poor sleep quality were independent risk factors for depression. Somatic symptoms and poor sleep quality are both the risk factors of anxiety and depression symptoms of infertile woman. And high educated (junior college degree or above) patients are more likely to be complicated with anxiety symptoms, while elderly patients (age>35) are prone to be complicated with depression symptoms. Public Library of Science 2023-04-13 /pmc/articles/PMC10101516/ /pubmed/37053254 http://dx.doi.org/10.1371/journal.pone.0284414 Text en © 2023 Wang et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Wang, Lingyan
Tang, Youyin
Wang, Yuyang
Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title_full Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title_fullStr Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title_full_unstemmed Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title_short Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study
title_sort predictors and incidence of depression and anxiety in women undergoing infertility treatment: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101516/
https://www.ncbi.nlm.nih.gov/pubmed/37053254
http://dx.doi.org/10.1371/journal.pone.0284414
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