Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis

SLC35A3 is considered an uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) transporter in mammals and regulates the branching of N-glycans. A missense mutation in SLC35A3 causes complex vertebral malformation (CVM) in cattle. However, the biological functions of SLC35A3 have not been fully clarif...

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Detalles Bibliográficos
Autores principales: Saito, Soichiro, Mizumoto, Shuji, Yonekura, Tsukasa, Yamashita, Rina, Nakano, Kenta, Okubo, Tadashi, Yamada, Shuhei, Okamura, Tadashi, Furuichi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101523/
https://www.ncbi.nlm.nih.gov/pubmed/37053259
http://dx.doi.org/10.1371/journal.pone.0284292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101523/
https://www.ncbi.nlm.nih.gov/pubmed/37053259
http://dx.doi.org/10.1371/journal.pone.0284292

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