Molekulare Pinzetten als Breitbandinhibitor viraler Infektionen

The SARS-CoV-2 pandemic once again highlighted the constant threat posed by viruses. Specific therapeutics are highly warranted, but their development is time consuming and cost intensive. Broad-spectrum antivirals provide a promising option for fast application to treat circulating or newly emerged...

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Detalles Bibliográficos
Autores principales: Weil, Tatjana, Münch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Wissenschaft · Special: Molekulare Medizin & Virologie
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101532/
https://www.ncbi.nlm.nih.gov/pubmed/37073322
http://dx.doi.org/10.1007/s12268-023-1906-y
Descripción
Sumario:The SARS-CoV-2 pandemic once again highlighted the constant threat posed by viruses. Specific therapeutics are highly warranted, but their development is time consuming and cost intensive. Broad-spectrum antivirals provide a promising option for fast application to treat circulating or newly emerged viruses. Here, we introduce molecular tweezers as broad-spectrum antivirals, which abrogate viral infection by directly targeting the viral membrane. Furthermore, we discuss the current stage of tweezer development to fight SARS-CoV-2 and other respiratory viruses.

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