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PIK3CA Mutation Is Associated with Poor Response to HER2-Targeted Therapy in Breast Cancer Patients

PURPOSE: Mutations in the PIK3CA gene occur frequently in breast cancer patients. Activating PIK3CA mutations confer resistance to human epidermal growth factor receptor 2 (HER2)–targeted treatments. In this study, we investigated whether PIK3CA mutations were correlated with treatment response or d...

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Detalles Bibliográficos
Autores principales:	Kim, Ju Won, Lim, Ah Reum, You, Ji Young, Lee, Jung Hyun, Song, Sung Eun, Lee, Nam Kwon, Jung, Seung Pil, Cho, Kyu Ran, Kim, Cheol Yong, Park, Kyong Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101795/ https://www.ncbi.nlm.nih.gov/pubmed/36097803 http://dx.doi.org/10.4143/crt.2022.221

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