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Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome

Neuroblastoma, the most frequent solid tumor in infants, shows very diverse outcomes from spontaneous regression to fatal disease. When these different tumors originate and how they evolve are not known. Here we quantify the somatic evolution of neuroblastoma by deep whole-genome sequencing, molecul...

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Detalles Bibliográficos
Autores principales: Körber, Verena, Stainczyk, Sabine A., Kurilov, Roma, Henrich, Kai-Oliver, Hero, Barbara, Brors, Benedikt, Westermann, Frank, Höfer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101850/
https://www.ncbi.nlm.nih.gov/pubmed/36973454
http://dx.doi.org/10.1038/s41588-023-01332-y