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NUDT22 promotes cancer growth through pyrimidine salvage

The NUDIX hydrolase NUDT22 converts UDP-glucose into glucose-1-phosphate and the pyrimidine nucleotide uridine monophosphate but a biological significance for this biochemical reaction has not yet been established. Glucose-1-phosphate is an important metabolite for energy and biomass production thro...

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Detalles Bibliográficos
Autores principales:	Walter, Melanie, Mayr, Florian, Hanna, Bishoy M. F., Cookson, Victoria, Mortusewicz, Oliver, Helleday, Thomas, Herr, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101856/ https://www.ncbi.nlm.nih.gov/pubmed/36871087 http://dx.doi.org/10.1038/s41388-023-02643-4

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