A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine

The microenvironment of chronic lymphocytic leukemia (CLL) cells in lymph nodes, spleen, and bone marrow provides survival, proliferation, and drug resistance signals. Therapies need to be effective in these compartments, and pre-clinical models of CLL that are used to test drug sensitivity must mim...

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Detalles Bibliográficos
Autores principales: Hermansen, Johanne U., Yin, Yanping, Urban, Aleksandra, Myklebust, Camilla V., Karlsen, Linda, Melvold, Katrine, Tveita, Anders A., Taskén, Kjetil, Munthe, Ludvig A., Tjønnfjord, Geir E., Skånland, Sigrid S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101987/
https://www.ncbi.nlm.nih.gov/pubmed/37055391
http://dx.doi.org/10.1038/s41420-023-01426-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101987/
https://www.ncbi.nlm.nih.gov/pubmed/37055391
http://dx.doi.org/10.1038/s41420-023-01426-w

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