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A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
The microenvironment of chronic lymphocytic leukemia (CLL) cells in lymph nodes, spleen, and bone marrow provides survival, proliferation, and drug resistance signals. Therapies need to be effective in these compartments, and pre-clinical models of CLL that are used to test drug sensitivity must mim...
Autores principales: | Hermansen, Johanne U., Yin, Yanping, Urban, Aleksandra, Myklebust, Camilla V., Karlsen, Linda, Melvold, Katrine, Tveita, Anders A., Taskén, Kjetil, Munthe, Ludvig A., Tjønnfjord, Geir E., Skånland, Sigrid S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101987/ https://www.ncbi.nlm.nih.gov/pubmed/37055391 http://dx.doi.org/10.1038/s41420-023-01426-w |
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