Helquat dyes targeting G-quadruplexes as a new class of anti-HIV-1 inhibitors

The secondary structure of nucleic acids containing quartets of guanines, termed G-quadruplexes, is known to regulate the transcription of many genes. Several G-quadruplexes can be formed in the HIV-1 long terminal repeat promoter region and their stabilization results in the inhibition of HIV-1 rep...

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Detalles Bibliográficos
Autores principales: Pávová, Marcela, Reyes-Gutiérrez, Paul Eduardo, Kozák, Jaroslav, Dobiaš, Juraj, Yurenko, Yevgen, Lepšík, Martin, Teplý, Filip, Weber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102027/
https://www.ncbi.nlm.nih.gov/pubmed/37055553
http://dx.doi.org/10.1038/s41598-023-33263-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102027/
https://www.ncbi.nlm.nih.gov/pubmed/37055553
http://dx.doi.org/10.1038/s41598-023-33263-3

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