Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis

Multiple sclerosis (MS) is a debilitating disease that requires prolonged treatment with often severe side effects. One experimental MS therapeutic currently under development is a single amino acid mutant of a plant peptide termed kalata B1, of the cyclotide family. Like all cyclotides, the therape...

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Detalles Bibliográficos
Autores principales: Jackson, Mark A., Xie, Jing, Nguyen, Linh T. T., Wang, Xiaohan, Yap, Kuok, Harvey, Peta J., Gilding, Edward K., Craik, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102037/
https://www.ncbi.nlm.nih.gov/pubmed/36930229
http://dx.doi.org/10.1007/s11248-023-00341-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102037/
https://www.ncbi.nlm.nih.gov/pubmed/36930229
http://dx.doi.org/10.1007/s11248-023-00341-1

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