Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways

BACKGROUND: Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies. Oxidative stress has been validated as a critical event involved in DOX-induced neurotoxicity. As a selective autophagy adaptor protein, p62 is reported to regulate Keap1-Nrf2-ARE antioxidant pathway in respo...

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Detalles Bibliográficos
Autores principales: Liao, Dehua, Shangguan, Danggang, Wu, Yi, Chen, Yun, Liu, Ni, Tang, Jingyi, Yao, Dunwu, Shi, Yingrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102057/
https://www.ncbi.nlm.nih.gov/pubmed/36949340
http://dx.doi.org/10.1007/s00213-023-06357-z

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