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Identification of the NA(+)/K(+)-ATPase α-Isoforms in Six Species of Poison Dart Frogs and their Sensitivity to Cardiotonic Steroids
Cardiotonic steroids (CTS) are a group of compounds known to be toxic due to their ability to inhibit the Na(+)/K(+)-ATPase (NKA), which is essential to maintain the balance of ions in animal cells. An evolutionary strategy of molecular adaptation to avoid self-intoxication acquired by CTS defended...
Autores principales: | Medina-Ortiz, Katherine, Navia, Felipe, Mosquera-Gil, Claudia, Sánchez, Adalberto, Sterling, Gonzalo, Fierro, Leonardo, Castaño, Santiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102066/ https://www.ncbi.nlm.nih.gov/pubmed/36877397 http://dx.doi.org/10.1007/s10886-023-01404-7 |
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