Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: impact of tumor stroma on penetration and efficacy

Since tumor stroma poses as a barrier to achieve efficacy of nanomedicines, it is essential to evaluate nano-chemotherapeutics in stroma-mimicking 3D models that reliably predict their behavior regarding these hurdles limiting efficacy. In this study, we evaluated the effect of paclitaxel-loaded pol...

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Detalles Bibliográficos
Autores principales: Priwitaningrum, Dwi L., Pednekar, Kunal, Gabriël, Alexandros V., Varela-Moreira, Aida A., Le Gac, Severine, Vellekoop, Ivo, Storm, Gert, Hennink, Wim E., Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102101/
https://www.ncbi.nlm.nih.gov/pubmed/36853438
http://dx.doi.org/10.1007/s13346-023-01310-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102101/
https://www.ncbi.nlm.nih.gov/pubmed/36853438
http://dx.doi.org/10.1007/s13346-023-01310-1

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