Structural insights into how augmin augments the mitotic spindle

Cell division critically requires amplification of microtubules (MTs) in the bipolar mitotic spindle. This relies on the filamentous augmin complex that enables MT branching. Studies by Gabel et al., Zupa et al. and Travis et al. describe consistent integrated atomic models of the extraordinarily fl...

Descripción completa

Detalles Bibliográficos
Autor principal: Manka, Szymon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102323/
https://www.ncbi.nlm.nih.gov/pubmed/37055387
http://dx.doi.org/10.1038/s41467-023-37625-3
_version_ 1785025669805113344
author Manka, Szymon W.
author_facet Manka, Szymon W.
author_sort Manka, Szymon W.
collection PubMed
description Cell division critically requires amplification of microtubules (MTs) in the bipolar mitotic spindle. This relies on the filamentous augmin complex that enables MT branching. Studies by Gabel et al., Zupa et al. and Travis et al. describe consistent integrated atomic models of the extraordinarily flexible augmin complex. Their work prompts the question: what is this flexibility really needed for?
format Online
Article
Text
id pubmed-10102323
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-101023232023-04-15 Structural insights into how augmin augments the mitotic spindle Manka, Szymon W. Nat Commun Comment Cell division critically requires amplification of microtubules (MTs) in the bipolar mitotic spindle. This relies on the filamentous augmin complex that enables MT branching. Studies by Gabel et al., Zupa et al. and Travis et al. describe consistent integrated atomic models of the extraordinarily flexible augmin complex. Their work prompts the question: what is this flexibility really needed for? Nature Publishing Group UK 2023-04-13 /pmc/articles/PMC10102323/ /pubmed/37055387 http://dx.doi.org/10.1038/s41467-023-37625-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Manka, Szymon W.
Structural insights into how augmin augments the mitotic spindle
title Structural insights into how augmin augments the mitotic spindle
title_full Structural insights into how augmin augments the mitotic spindle
title_fullStr Structural insights into how augmin augments the mitotic spindle
title_full_unstemmed Structural insights into how augmin augments the mitotic spindle
title_short Structural insights into how augmin augments the mitotic spindle
title_sort structural insights into how augmin augments the mitotic spindle
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102323/
https://www.ncbi.nlm.nih.gov/pubmed/37055387
http://dx.doi.org/10.1038/s41467-023-37625-3
work_keys_str_mv AT mankaszymonw structuralinsightsintohowaugminaugmentsthemitoticspindle

Ejemplares similares