Advances and challenges in CRISPR-based real-time imaging of dynamic genome organization

Nuclear chromosome compaction is non-random and dynamic. The spatial distance among genomic elements instantly modulates transcription. Visualization of the genome organization in the cell nucleus is essential to understand nuclear function. In addition to cell type-dependent organization, high-reso...

Descripción completa

Detalles Bibliográficos
Autores principales: Thuma, Jenna, Chung, Yu-Chieh, Tu, Li-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102487/
https://www.ncbi.nlm.nih.gov/pubmed/37065447
http://dx.doi.org/10.3389/fmolb.2023.1173545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102487/
https://www.ncbi.nlm.nih.gov/pubmed/37065447
http://dx.doi.org/10.3389/fmolb.2023.1173545

Ejemplares similares