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Advances and challenges in CRISPR-based real-time imaging of dynamic genome organization
Nuclear chromosome compaction is non-random and dynamic. The spatial distance among genomic elements instantly modulates transcription. Visualization of the genome organization in the cell nucleus is essential to understand nuclear function. In addition to cell type-dependent organization, high-reso...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102487/ https://www.ncbi.nlm.nih.gov/pubmed/37065447 http://dx.doi.org/10.3389/fmolb.2023.1173545 |