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A mass balance study of [(14)C]SHR6390 (dalpiciclib), a selective and potent CDK4/6 inhibitor in humans
SHR6390 (dalpiciclib) is a selective and effective cyclin-dependent kinase (CDK) 4/6 inhibitor and an effective cancer therapeutic agent. On 31 December 2021, the new drug application was approved by National Medical Product Administration (NMPA). The metabolism, mass balance, and pharmacokinetics o...
Autores principales: | Zhang, Hua, Yan, Shu, Zhan, Yan, Ma, Sheng, Bian, Yicong, Li, Shaorong, Tian, Junjun, Li, Guangze, Zhong, Dafang, Diao, Xingxing, Miao, Liyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102643/ https://www.ncbi.nlm.nih.gov/pubmed/37063263 http://dx.doi.org/10.3389/fphar.2023.1116073 |
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