Cargando…

Phase I Study of the Liposomal Formulation of Eribulin (E7389-LF): Results from the Advanced Gastric Cancer Expansion Cohort

PURPOSE: In the dose-expansion part of this open-label, phase I study, we explored the efficacy and safety of E7389-LF (liposomal formulation of eribulin) in Japanese patients with advanced gastric cancer. PATIENTS AND METHODS: Patients with advanced gastric cancer who had been previously treated wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shitara, Kohei, Hirao, Motohiro, Iwasa, Satoru, Oshima, Takashi, Komatsu, Yoshito, Kawazoe, Akihito, Sato, Yasuyoshi, Hamakawa, Takuya, Yonemori, Kan, Machida, Nozomu, Yuki, Satoshi, Suzuki, Takuya, Okumura, Shiori, Takase, Takao, Semba, Taro, Zimmermann, Bob, Teng, Angela, Yamaguchi, Kensei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Clinical Trials: Targeted Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102841/ https://www.ncbi.nlm.nih.gov/pubmed/36730323 http://dx.doi.org/10.1158/1078-0432.CCR-22-3027

Ejemplares similares

Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid Tumors
por: Sato, Jun, et al.
Publicado: (2022)

Phase Ib/II Study of a Liposomal Formulation of Eribulin (E7389-LF) plus Nivolumab in Patients with Advanced Solid Tumors: Results from Phase Ib
por: Ida, Hanae, et al.
Publicado: (2023)

Liposomal eribulin for advanced adenoid cystic carcinoma, gastric cancer, esophageal cancer, and small cell lung cancer
por: Udagawa, Hibiki, et al.
Publicado: (2022)

Indirect Decompression Failure After Lateral Lumbar Interbody Fusion—Reported Failures and Predictive Factors: Systematic Review
por: Kirnaz, Sertac, et al.
Publicado: (2020)

Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
por: Niwa, Yuki, et al.
Publicado: (2023)

Next-generation sequencing and biomarkers for gastric cancer: what is the future?
por: Kawazoe, Akihito, et al.
Publicado: (2019)

Systemic Therapy for Soft Tissue Sarcoma: Proposals for the Optimal Use of Pazopanib, Trabectedin, and Eribulin
por: Kawai, Akira, et al.
Publicado: (2017)

Mind Perception Is the Essence of Morality
por: Gray, Kurt, et al.
Publicado: (2012)

Neuroethics: A New Way of Doing Ethics
por: Levy, Neil
Publicado: (2011)

A Life Worth Giving? The Threshold for Permissible Withdrawal of Life Support From Disabled Newborn Infants
por: Wilkinson, Dominic James
Publicado: (2011)

Just How Cognitive Is “Cognitive Enhancement”? On the Significance of Emotions in University Students' Experiences with Study Drugs
por: Vrecko, Scott
Publicado: (2013)

Troubled sleep: Night waking, breastfeeding and parent–offspring conflict
por: Haig, David
Publicado: (2014)

Thinking Ahead on Deep Brain Stimulation: An Analysis of the Ethical Implications of a Developing Technology
por: Johansson, Veronica, et al.
Publicado: (2014)

Brave New Love: The Threat of High-Tech “Conversion” Therapy and the Bio-Oppression of Sexual Minorities
por: Earp, Brian D., et al.
Publicado: (2014)

Patient and Citizen Participation in Health: The Need for Improved Ethical Support
por: Williamson, Laura
Publicado: (2014)

Ethics of Clinical Science in a Public Health Emergency: Drug Discovery at the Bedside
por: Edwards, Sarah J. L.
Publicado: (2013)

Treating Patients as Persons: A Capabilities Approach to Support Delivery of Person-Centered Care
por: Entwistle, Vikki A., et al.
Publicado: (2013)

The Use of Deception in Public Health Behavioral Intervention Trials: A Case Study of Three Online Alcohol Trials
por: McCambridge, Jim, et al.
Publicado: (2013)

If I Could Just Stop Loving You: Anti-Love Biotechnology and the Ethics of a Chemical Breakup
por: Earp, Brian D., et al.
Publicado: (2013)

A Threat to Autonomy? The Intrusion of Predictive Brain Implants
por: Gilbert, Frederic
Publicado: (2015)

A prospective study of macrophage migration inhibitory factor as a marker of inflammatory detection
por: Zhang, Chao, et al.
Publicado: (2009)

Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework
por: Evitt, Niklaus H., et al.
Publicado: (2015)

Developmental plasticity: Bridging research in evolution and human health
por: Lea, Amanda J, et al.
Publicado: (2018)

The ER membrane protein complex is a transmembrane domain insertase
por: Guna, Alina, et al.
Publicado: (2017)

Why and how to use virtual reality to study human social interaction: The challenges of exploring a new research landscape
por: Pan, Xueni, et al.
Publicado: (2018)

Just Policy? An Ethical Analysis of Early Intervention Policy Guidance
por: Mortimer, Rose, et al.
Publicado: (2018)

Withdrawal Aversion and the Equivalence Test
por: Wilkinson, Dominic, et al.
Publicado: (2019)

Update on the target structures of SARS-CoV-2: A systematic review
por: Prajapat, Manisha, et al.
Publicado: (2020)

When Thinking is Doing: Responsibility for BCI-Mediated Action
por: Rainey, Stephen, et al.
Publicado: (2020)

Frailty Triage: Is Rationing Intensive Medical Treatment on the Grounds of Frailty Ethical?
por: Wilkinson, Dominic J. C.
Publicado: (2020)

Targeting immunometabolism to treat COVID-19
por: O’Carroll, Shane M, et al.
Publicado: (2021)

Viruses, Vaccines, and COVID-19: Explaining and Improving Risky Decision-making
por: Reyna, Valerie F., et al.
Publicado: (2021)

Design Bioethics: A Theoretical Framework and Argument for Innovation in Bioethics Research
por: Pavarini, Gabriela, et al.
Publicado: (2021)

Harnessing immunometabolism for cardiovascular health and cancer therapy
por: Markovska, Angela, et al.
Publicado: (2021)

Immuno-antibiotics: targeting microbial metabolic pathways sensed by unconventional T cells
por: Eberl, Matthias, et al.
Publicado: (2021)

Adaptive immunity and vaccination – iron in the spotlight
por: Preston, Alexandra E, et al.
Publicado: (2021)

α2-3 Sialic acid binding and uptake by human monocyte-derived dendritic cells alters metabolism and cytokine release and initiates tolerizing T cell programming
por: Lübbers, Joyce, et al.
Publicado: (2021)

Editor’s Note: Relates to: ‘Immuno-antibiotics: targeting microbial metabolic pathways sensed by unconventional T cells’
por: Eberl, Matthias, et al.
Publicado: (2021)

Transthyretin amyloid deposition in ligamentum flavum (LF) is significantly correlated with LF and epidural fat hypertrophy in patients with lumbar spinal stenosis
por: Maeda, Kazuya, et al.
Publicado: (2023)

The New Era of Immunotherapy in Gastric Cancer
por: Takei, Shogo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pov18i8g7evmo1mfrtu35ld2ks