DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Metastases from primary prostate cancers to rare locations, such as the brain, are becoming more common due to longer life expectancy resulting from improved treatments. Epigenetic dysregulation is a feature of primary prostate cancer, and distinct DNA methylation profiles have been shown to be asso...

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Detalles Bibliográficos
Autores principales: Gallon, John, Rodriguez-Calero, Antonio, Benjak, Andrej, Akhoundova, Dilara, Maletti, Sina, Amstutz, Ursula, Hewer, Ekkehard, Genitsch, Vera, Fleischmann, Achim, Rushing, Elisabeth J., Grobholz, Rainer, Fischer, Ingeborg, Jochum, Wolfram, Cathomas, Gieri, Osunkoya, Adeboye O., Bubendorf, Lukas, Moch, Holger, Thalmann, George, Feng, Felix Y., Gillessen, Silke, Ng, Charlotte K.Y., Rubin, Mark A., Piscuoglio, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Genome and Epigenome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102845/
https://www.ncbi.nlm.nih.gov/pubmed/36749655
http://dx.doi.org/10.1158/0008-5472.CAN-22-2236

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