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Integrated causal-predictive machine learning models for tropical cyclone epidemiology

Strategic preparedness reduces the adverse health impacts of hurricanes and tropical storms, referred to collectively as tropical cyclones (TCs), but its protective impact could be enhanced by a more comprehensive and rigorous characterization of TC epidemiology. To generate the insights and tools n...

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Autores principales: Nethery, Rachel C, Katz-Christy, Nina, Kioumourtzoglou, Marianthi-Anna, Parks, Robbie M, Schumacher, Andrea, Anderson, G Brooke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102905/
https://www.ncbi.nlm.nih.gov/pubmed/34962265
http://dx.doi.org/10.1093/biostatistics/kxab047
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author Nethery, Rachel C
Katz-Christy, Nina
Kioumourtzoglou, Marianthi-Anna
Parks, Robbie M
Schumacher, Andrea
Anderson, G Brooke
author_facet Nethery, Rachel C
Katz-Christy, Nina
Kioumourtzoglou, Marianthi-Anna
Parks, Robbie M
Schumacher, Andrea
Anderson, G Brooke
author_sort Nethery, Rachel C
collection PubMed
description Strategic preparedness reduces the adverse health impacts of hurricanes and tropical storms, referred to collectively as tropical cyclones (TCs), but its protective impact could be enhanced by a more comprehensive and rigorous characterization of TC epidemiology. To generate the insights and tools necessary for high-precision TC preparedness, we introduce a machine learning approach that standardizes estimation of historic TC health impacts, discovers common patterns and sources of heterogeneity in those health impacts, and enables identification of communities at highest health risk for future TCs. The model integrates (i) a causal inference component to quantify the immediate health impacts of recent historic TCs at high spatial resolution and (ii) a predictive component that captures how TC meteorological features and socioeconomic/demographic characteristics of impacted communities are associated with health impacts. We apply it to a rich data platform containing detailed historic TC exposure information and records of all-cause mortality and cardiovascular- and respiratory-related hospitalization among Medicare recipients. We report a high degree of heterogeneity in the acute health impacts of historic TCs, both within and across TCs, and, on average, substantial TC-attributable increases in respiratory hospitalizations. TC-sustained windspeeds are found to be the primary driver of mortality and respiratory risks.
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spelling pubmed-101029052023-04-15 Integrated causal-predictive machine learning models for tropical cyclone epidemiology Nethery, Rachel C Katz-Christy, Nina Kioumourtzoglou, Marianthi-Anna Parks, Robbie M Schumacher, Andrea Anderson, G Brooke Biostatistics Article Strategic preparedness reduces the adverse health impacts of hurricanes and tropical storms, referred to collectively as tropical cyclones (TCs), but its protective impact could be enhanced by a more comprehensive and rigorous characterization of TC epidemiology. To generate the insights and tools necessary for high-precision TC preparedness, we introduce a machine learning approach that standardizes estimation of historic TC health impacts, discovers common patterns and sources of heterogeneity in those health impacts, and enables identification of communities at highest health risk for future TCs. The model integrates (i) a causal inference component to quantify the immediate health impacts of recent historic TCs at high spatial resolution and (ii) a predictive component that captures how TC meteorological features and socioeconomic/demographic characteristics of impacted communities are associated with health impacts. We apply it to a rich data platform containing detailed historic TC exposure information and records of all-cause mortality and cardiovascular- and respiratory-related hospitalization among Medicare recipients. We report a high degree of heterogeneity in the acute health impacts of historic TCs, both within and across TCs, and, on average, substantial TC-attributable increases in respiratory hospitalizations. TC-sustained windspeeds are found to be the primary driver of mortality and respiratory risks. Oxford University Press 2021-12-28 /pmc/articles/PMC10102905/ /pubmed/34962265 http://dx.doi.org/10.1093/biostatistics/kxab047 Text en © The Author 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Nethery, Rachel C
Katz-Christy, Nina
Kioumourtzoglou, Marianthi-Anna
Parks, Robbie M
Schumacher, Andrea
Anderson, G Brooke
Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title_full Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title_fullStr Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title_full_unstemmed Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title_short Integrated causal-predictive machine learning models for tropical cyclone epidemiology
title_sort integrated causal-predictive machine learning models for tropical cyclone epidemiology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102905/
https://www.ncbi.nlm.nih.gov/pubmed/34962265
http://dx.doi.org/10.1093/biostatistics/kxab047
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