Strategic application of imaging in DMOAD clinical trials: focus on eligibility, drug delivery, and semiquantitative assessment of structural progression

Despite decades of research efforts and multiple clinical trials aimed at discovering efficacious disease-modifying osteoarthritis (OA) drugs (DMOAD), we still do not have a drug that shows convincing scientific evidence to be approved as an effective DMOAD. It has been suggested these DMOAD clinica...

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Detalles Bibliográficos
Autores principales: Guermazi, Ali, Roemer, Frank W., Crema, Michel D., Jarraya, Mohamed, Mobasheri, Ali, Hayashi, Daichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Addressing the Challenges Associated with the Development, Testing and Approval of Novel Therapeutics for Osteoarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103249/
https://www.ncbi.nlm.nih.gov/pubmed/37063459
http://dx.doi.org/10.1177/1759720X231165558

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