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In Vivo RNA Delivery to Hematopoietic Stem and Progenitor Cells via Targeted Lipid Nanoparticles

[Image: see text] Ex vivo autologous hematopoietic stem cell (HSC) gene therapy has provided new therapies for the treatment of hematological disorders. However, these therapies have several limitations owing to the manufacturing complexities and toxicity resulting from required conditioning regimen...

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Detalles Bibliográficos
Autores principales:	Shi, Dennis, Toyonaga, Sho, Anderson, Daniel G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103292/ https://www.ncbi.nlm.nih.gov/pubmed/36988645 http://dx.doi.org/10.1021/acs.nanolett.3c00304

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