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Genetic variants of Dabie bandavirus: classification and biological/clinical implications
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV), a novel Bandavirus in the family Phenuiviridae. The first case of SFTS was reported in China, followed by cases in Japan, South Korea, Taiwan and Vietnam. With clinical manifestatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103499/ https://www.ncbi.nlm.nih.gov/pubmed/37060090 http://dx.doi.org/10.1186/s12985-023-02033-y |
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author | Liu, Bingyan Zhu, Jie He, Tengfei Zhang, Zhenhua |
author_facet | Liu, Bingyan Zhu, Jie He, Tengfei Zhang, Zhenhua |
author_sort | Liu, Bingyan |
collection | PubMed |
description | Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV), a novel Bandavirus in the family Phenuiviridae. The first case of SFTS was reported in China, followed by cases in Japan, South Korea, Taiwan and Vietnam. With clinical manifestations including fever, leukopenia, thrombocytopenia, and gastrointestinal symptoms, SFTS has a fatality rate of approximately 10%. In recent years, an increasing number of viral strains have been isolated and sequenced, and several research groups have attempted to classify the different genotypes of DBV. Additionally, accumulating evidence indicates certain correlations between the genetic makeup and biological/clinical manifestations of the virus. Here, we attempted to evaluate the genetic classification of different groups, align the genotypic nomenclature in different studies, summarize the distribution of different genotypes, and review the biological and clinical implications of DBV genetic variations. |
format | Online Article Text |
id | pubmed-10103499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-101034992023-04-15 Genetic variants of Dabie bandavirus: classification and biological/clinical implications Liu, Bingyan Zhu, Jie He, Tengfei Zhang, Zhenhua Virol J Review Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV), a novel Bandavirus in the family Phenuiviridae. The first case of SFTS was reported in China, followed by cases in Japan, South Korea, Taiwan and Vietnam. With clinical manifestations including fever, leukopenia, thrombocytopenia, and gastrointestinal symptoms, SFTS has a fatality rate of approximately 10%. In recent years, an increasing number of viral strains have been isolated and sequenced, and several research groups have attempted to classify the different genotypes of DBV. Additionally, accumulating evidence indicates certain correlations between the genetic makeup and biological/clinical manifestations of the virus. Here, we attempted to evaluate the genetic classification of different groups, align the genotypic nomenclature in different studies, summarize the distribution of different genotypes, and review the biological and clinical implications of DBV genetic variations. BioMed Central 2023-04-14 /pmc/articles/PMC10103499/ /pubmed/37060090 http://dx.doi.org/10.1186/s12985-023-02033-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Liu, Bingyan Zhu, Jie He, Tengfei Zhang, Zhenhua Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title | Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title_full | Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title_fullStr | Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title_full_unstemmed | Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title_short | Genetic variants of Dabie bandavirus: classification and biological/clinical implications |
title_sort | genetic variants of dabie bandavirus: classification and biological/clinical implications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103499/ https://www.ncbi.nlm.nih.gov/pubmed/37060090 http://dx.doi.org/10.1186/s12985-023-02033-y |
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