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Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021

Between November and December 2021, the first ever recorded outbreak of enteroinvasive Escherichia coli in Denmark occurred at national scale. We describe the investigation of this outbreak, which was initially recognised in early December 2021. A total of 88 cases (58 female; 30 male) with a median...

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Autores principales: Torpdahl, Mia, White, Emily Dibba, Schjørring, Susanne, Søby, Malene, Engberg, Jørgen, Engsbro, Anne Line, Holt, Hanne M, Lemming, Lars, Lützen, Lisbeth, Olesen, Bente, Coia, John E, Kjelsø, Charlotte, Müller, Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103548/
https://www.ncbi.nlm.nih.gov/pubmed/37052680
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.15.2200572
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author Torpdahl, Mia
White, Emily Dibba
Schjørring, Susanne
Søby, Malene
Engberg, Jørgen
Engsbro, Anne Line
Holt, Hanne M
Lemming, Lars
Lützen, Lisbeth
Olesen, Bente
Coia, John E
Kjelsø, Charlotte
Müller, Luise
author_facet Torpdahl, Mia
White, Emily Dibba
Schjørring, Susanne
Søby, Malene
Engberg, Jørgen
Engsbro, Anne Line
Holt, Hanne M
Lemming, Lars
Lützen, Lisbeth
Olesen, Bente
Coia, John E
Kjelsø, Charlotte
Müller, Luise
author_sort Torpdahl, Mia
collection PubMed
description Between November and December 2021, the first ever recorded outbreak of enteroinvasive Escherichia coli in Denmark occurred at national scale. We describe the investigation of this outbreak, which was initially recognised in early December 2021. A total of 88 cases (58 female; 30 male) with a median age of 52 years (range: 0–91) were detected by PCR-based diagnostic methods. Case ascertainment was complicated by current culture-free diagnostic procedures, with only 34 cases confirmed by culture, serotyping and whole genome sequencing. Isolates from cases grouped into two serotypes (O136:H7 and O96:H19), which was supported by whole-genome-sequence-phylogeny, also yielding two clusters. Interviews of 42 cases and traceback investigation pointed towards consumption of ready-to-eat salads as the outbreak cause. While the ready-to-eat salads comprised different vegetables, imported spring onions were the only common ingredient and thus the likely source. Environmental investigations failed to recover outbreak strains. This report highlights the value of fast typing (here O-typing) to confirm cases in an outbreak situation. Timely communication and data sharing are also important, and were facilitated by the national collaboration between relevant laboratories, the public health institute and the veterinary and food administration. High hygiene standards for imported fresh vegetables intended for ready-to-eat products are essential.
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spelling pubmed-101035482023-04-15 Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021 Torpdahl, Mia White, Emily Dibba Schjørring, Susanne Søby, Malene Engberg, Jørgen Engsbro, Anne Line Holt, Hanne M Lemming, Lars Lützen, Lisbeth Olesen, Bente Coia, John E Kjelsø, Charlotte Müller, Luise Euro Surveill Outbreaks Between November and December 2021, the first ever recorded outbreak of enteroinvasive Escherichia coli in Denmark occurred at national scale. We describe the investigation of this outbreak, which was initially recognised in early December 2021. A total of 88 cases (58 female; 30 male) with a median age of 52 years (range: 0–91) were detected by PCR-based diagnostic methods. Case ascertainment was complicated by current culture-free diagnostic procedures, with only 34 cases confirmed by culture, serotyping and whole genome sequencing. Isolates from cases grouped into two serotypes (O136:H7 and O96:H19), which was supported by whole-genome-sequence-phylogeny, also yielding two clusters. Interviews of 42 cases and traceback investigation pointed towards consumption of ready-to-eat salads as the outbreak cause. While the ready-to-eat salads comprised different vegetables, imported spring onions were the only common ingredient and thus the likely source. Environmental investigations failed to recover outbreak strains. This report highlights the value of fast typing (here O-typing) to confirm cases in an outbreak situation. Timely communication and data sharing are also important, and were facilitated by the national collaboration between relevant laboratories, the public health institute and the veterinary and food administration. High hygiene standards for imported fresh vegetables intended for ready-to-eat products are essential. European Centre for Disease Prevention and Control (ECDC) 2023-04-13 /pmc/articles/PMC10103548/ /pubmed/37052680 http://dx.doi.org/10.2807/1560-7917.ES.2023.28.15.2200572 Text en This article is copyright of the authors or their affiliated institutions, 2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Outbreaks
Torpdahl, Mia
White, Emily Dibba
Schjørring, Susanne
Søby, Malene
Engberg, Jørgen
Engsbro, Anne Line
Holt, Hanne M
Lemming, Lars
Lützen, Lisbeth
Olesen, Bente
Coia, John E
Kjelsø, Charlotte
Müller, Luise
Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title_full Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title_fullStr Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title_full_unstemmed Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title_short Imported spring onions related to the first recorded outbreak of enteroinvasive Escherichia coli in Denmark, November to December 2021
title_sort imported spring onions related to the first recorded outbreak of enteroinvasive escherichia coli in denmark, november to december 2021
topic Outbreaks
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103548/
https://www.ncbi.nlm.nih.gov/pubmed/37052680
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.15.2200572
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