Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency

Creatine transporter deficiency (CTD), a leading cause of intellectual disability is a result of the mutation in the gene encoding the creatine transporter SLC6A8, which prevents creatine uptake into the brain, causing mental retardation, expressive speech and language delay, autistic-like behavior...

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Detalles Bibliográficos
Autores principales: Mabondzo, Aloïse, Harati, Rania, Broca-Brisson, Léa, Guyot, Anne-Cécile, Costa, Narciso, Cacciante, Francesco, Putignano, Elena, Baroncelli, Laura, Skelton, Matthew R., Saab, Cathy, Martini, Emmanuelle, Benech, Henri, Joudinaud, Thomas, Gaillard, Jean-Charles, Armengaud, Jean, Hamoudi, Rifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103630/
https://www.ncbi.nlm.nih.gov/pubmed/37063368
http://dx.doi.org/10.3389/fnmol.2023.1118707

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