Virus update for the M2 “mac-in-touch”

While HIV-1 infection of macrophages plays a major role in viral persistence and pathogenesis, how HIV-1 transfers from infected T cells to macrophages remains elusive. In this issue, Mascarau et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202205103) demonstrate how macrophage polarization...

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Detalles Bibliográficos
Autor principal: Naghavi, Mojgan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103641/
https://www.ncbi.nlm.nih.gov/pubmed/37043190
http://dx.doi.org/10.1083/jcb.202303016
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author Naghavi, Mojgan H.
author_facet Naghavi, Mojgan H.
author_sort Naghavi, Mojgan H.
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description While HIV-1 infection of macrophages plays a major role in viral persistence and pathogenesis, how HIV-1 transfers from infected T cells to macrophages remains elusive. In this issue, Mascarau et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202205103) demonstrate how macrophage polarization drives their ability to fuse with HIV-1 infected T cells via the CD81/RhoA-ROCK/Myosin axis.
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spelling pubmed-101036412023-10-12 Virus update for the M2 “mac-in-touch” Naghavi, Mojgan H. J Cell Biol Spotlight While HIV-1 infection of macrophages plays a major role in viral persistence and pathogenesis, how HIV-1 transfers from infected T cells to macrophages remains elusive. In this issue, Mascarau et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202205103) demonstrate how macrophage polarization drives their ability to fuse with HIV-1 infected T cells via the CD81/RhoA-ROCK/Myosin axis. Rockefeller University Press 2023-04-12 /pmc/articles/PMC10103641/ /pubmed/37043190 http://dx.doi.org/10.1083/jcb.202303016 Text en © 2023 Naghavi https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Naghavi, Mojgan H.
Virus update for the M2 “mac-in-touch”
title Virus update for the M2 “mac-in-touch”
title_full Virus update for the M2 “mac-in-touch”
title_fullStr Virus update for the M2 “mac-in-touch”
title_full_unstemmed Virus update for the M2 “mac-in-touch”
title_short Virus update for the M2 “mac-in-touch”
title_sort virus update for the m2 “mac-in-touch”
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103641/
https://www.ncbi.nlm.nih.gov/pubmed/37043190
http://dx.doi.org/10.1083/jcb.202303016
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