PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion

Distinguishing key factors that drive the switch from indolent to invasive disease will make a significant impact on guiding the treatment of prostate cancer (PCa) patients. Here, we identify a novel signaling pathway linking hypoxia and PIM1 kinase to the actin cytoskeleton and cell motility. An un...

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Detalles Bibliográficos
Autores principales: Jensen, Corbin C., Clements, Amber N., Liou, Hope, Ball, Lauren E., Bethard, Jennifer R., Langlais, Paul R., Toth, Rachel K., Chauhan, Shailender S., Casillas, Andrea L., Daulat, Sohail R., Kraft, Andrew S., Cress, Anne E., Miranti, Cindy K., Mouneimne, Ghassan, Rogers, Greg C., Warfel, Noel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103708/
https://www.ncbi.nlm.nih.gov/pubmed/37042842
http://dx.doi.org/10.1083/jcb.202208136

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