Cargando…

Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation

Maternal anti-SS-A antibodies may cause complete atrioventricular block or myocardial damage in a fetus. Effective treatment for this has not been established. Although antenatal steroids may be a treatment option for anti-SS-A antibody-related myocarditis or atrioventricular block, a complete atrio...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishii, Kuniya, Horikoshi, Tsuguhiro, Kanai, Masayo, Ishiguro, Akio, Iwamoto, Yoichi, Ishido, Hirotaka, Kikuchi, Akihiko, Masutani, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103817/
https://www.ncbi.nlm.nih.gov/pubmed/37065348
http://dx.doi.org/10.7759/cureus.36203
_version_ 1785025930082648064
author Ishii, Kuniya
Horikoshi, Tsuguhiro
Kanai, Masayo
Ishiguro, Akio
Iwamoto, Yoichi
Ishido, Hirotaka
Kikuchi, Akihiko
Masutani, Satoshi
author_facet Ishii, Kuniya
Horikoshi, Tsuguhiro
Kanai, Masayo
Ishiguro, Akio
Iwamoto, Yoichi
Ishido, Hirotaka
Kikuchi, Akihiko
Masutani, Satoshi
author_sort Ishii, Kuniya
collection PubMed
description Maternal anti-SS-A antibodies may cause complete atrioventricular block or myocardial damage in a fetus. Effective treatment for this has not been established. Although antenatal steroids may be a treatment option for anti-SS-A antibody-related myocarditis or atrioventricular block, a complete atrioventricular block is usually considered irreversible once established. Previous reports have indicated that, in cases where antenatal steroids were effective for atrioventricular block, they were administered earlier in the pregnancy. Here we present a case where maternal steroid administration initiated from 27 weeks, which is beyond the recommended optimal treatment period, was effective in altering a complete atrioventricular block to a grade I atrioventricular block.
format Online
Article
Text
id pubmed-10103817
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-101038172023-04-15 Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation Ishii, Kuniya Horikoshi, Tsuguhiro Kanai, Masayo Ishiguro, Akio Iwamoto, Yoichi Ishido, Hirotaka Kikuchi, Akihiko Masutani, Satoshi Cureus Cardiology Maternal anti-SS-A antibodies may cause complete atrioventricular block or myocardial damage in a fetus. Effective treatment for this has not been established. Although antenatal steroids may be a treatment option for anti-SS-A antibody-related myocarditis or atrioventricular block, a complete atrioventricular block is usually considered irreversible once established. Previous reports have indicated that, in cases where antenatal steroids were effective for atrioventricular block, they were administered earlier in the pregnancy. Here we present a case where maternal steroid administration initiated from 27 weeks, which is beyond the recommended optimal treatment period, was effective in altering a complete atrioventricular block to a grade I atrioventricular block. Cureus 2023-03-15 /pmc/articles/PMC10103817/ /pubmed/37065348 http://dx.doi.org/10.7759/cureus.36203 Text en Copyright © 2023, Ishii et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Ishii, Kuniya
Horikoshi, Tsuguhiro
Kanai, Masayo
Ishiguro, Akio
Iwamoto, Yoichi
Ishido, Hirotaka
Kikuchi, Akihiko
Masutani, Satoshi
Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title_full Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title_fullStr Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title_full_unstemmed Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title_short Transient Recovery of Complete Atrioventricular Block Due to Maternal Anti-SS-A Antibody Through Antenatal Steroid Administration After 27 Weeks of Gestation
title_sort transient recovery of complete atrioventricular block due to maternal anti-ss-a antibody through antenatal steroid administration after 27 weeks of gestation
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103817/
https://www.ncbi.nlm.nih.gov/pubmed/37065348
http://dx.doi.org/10.7759/cureus.36203
work_keys_str_mv AT ishiikuniya transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT horikoshitsuguhiro transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT kanaimasayo transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT ishiguroakio transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT iwamotoyoichi transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT ishidohirotaka transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT kikuchiakihiko transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation
AT masutanisatoshi transientrecoveryofcompleteatrioventricularblockduetomaternalantissaantibodythroughantenatalsteroidadministrationafter27weeksofgestation