Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect

The general consensus is that increases in neuronal activity in the anterior cingulate cortex (ACC) contribute to pain’s negative affect. Here, using in vivo imaging of neuronal calcium dynamics in mice, we report that nitrous oxide, a general anesthetic that reduces pain affect, paradoxically, incr...

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Detalles Bibliográficos
Autores principales: Weinrich, Jarret AP, Liu, Cindy D, Jewell, Madison E, Andolina, Christopher R, Bernstein, Mollie X, Benitez, Jorge, Rodriguez-Rosado, Sian, Braz, Joao M, Maze, Mervyn, Nemenov, Mikhail I, Basbaum, Allan I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104003/
https://www.ncbi.nlm.nih.gov/pubmed/37066151
http://dx.doi.org/10.1101/2023.04.03.534475

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