SFyNCS detects oncogenic fusions involving non-coding sequences in cancer

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Fusion genes are well-known cancer drivers. However, very few known oncogenic fusions involve non-coding sequences. We develop SFyNCS with superior performance to detect fusions of both protein-coding genes and non-coding sequences from transcriptomic sequencing data. We validate fusions using somat...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaoming, Luan, Jingyun, Yu, Anqi, Lee-Hassett, Anna, Miao, Yuxuan, Yang, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104044/
https://www.ncbi.nlm.nih.gov/pubmed/37066382
http://dx.doi.org/10.1101/2023.04.03.535462
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