Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism

Eukaryotic reverse transcriptases (RTs) can have essential or deleterious roles in normal human physiology and disease. Compared to well-studied helicases, it remains unclear how RTs overcome the ubiquitous RNA structural barriers during reverse transcription. Herein, we describe the development of...

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Detalles Bibliográficos
Autores principales: Shaw, Alan, Craig, Jonathan M., Amiri, Hossein, Kim, Jeonghoon, Upton, Heather E., Pimentel, Sydney C., Huang, Jesse R., Marqusee, Susan, Collins, Kathleen, Gundlach, Jens H., Bustamante, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104057/
https://www.ncbi.nlm.nih.gov/pubmed/37066208
http://dx.doi.org/10.1101/2023.04.05.535757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104057/
https://www.ncbi.nlm.nih.gov/pubmed/37066208
http://dx.doi.org/10.1101/2023.04.05.535757

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