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Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism
Eukaryotic reverse transcriptases (RTs) can have essential or deleterious roles in normal human physiology and disease. Compared to well-studied helicases, it remains unclear how RTs overcome the ubiquitous RNA structural barriers during reverse transcription. Herein, we describe the development of...
Autores principales: | Shaw, Alan, Craig, Jonathan M., Amiri, Hossein, Kim, Jeonghoon, Upton, Heather E., Pimentel, Sydney C., Huang, Jesse R., Marqusee, Susan, Collins, Kathleen, Gundlach, Jens H., Bustamante, Carlos J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104057/ https://www.ncbi.nlm.nih.gov/pubmed/37066208 http://dx.doi.org/10.1101/2023.04.05.535757 |
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