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Systematic visualisation of molecular QTLs reveals variant mechanisms at GWAS loci

Splicing quantitative trait loci (QTLs) have been implicated as a common mechanism underlying complex trait associations. However, utilising splicing QTLs in target discovery and prioritisation has been challenging due to extensive data normalisation which often renders the direction of the genetic...

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Detalles Bibliográficos
Autores principales:	Kerimov, Nurlan, Tambets, Ralf, Hayhurst, James D., Rahu, Ida, Kolberg, Peep, Raudvere, Uku, Kuzmin, Ivan, Chowdhary, Anshika, Vija, Andreas, Teras, Hans J., Kanai, Masahiro, Ulirsch, Jacob, Ryten, Mina, Hardy, John, Guelfi, Sebastian, Trabzuni, Daniah, Kim-Hellmuth, Sarah, Rayner, Will, Finucane, Hilary, Peterson, Hedi, Mosaku, Abayomi, Parkinson, Helen, Alasoo, Kaur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104061/ https://www.ncbi.nlm.nih.gov/pubmed/37066341 http://dx.doi.org/10.1101/2023.04.06.535816

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