TREM2 mediates MHCII-associated CD4(+) T cell response against gliomas

Triggering receptor expressed on myeloid cells 2 (TREM2) was recently highlighted as a novel immune suppressive marker in peripheral tumors. The aim of this study was to characterize TREM2 expression in gliomas and investigate its contribution in glioma progression by using Trem2(−/−) mouse line. Ou...

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Detalles Bibliográficos
Autores principales: Zheng, Jiaying, Wang, Lingxiao, Zhao, Shunyi, Zhang, Wenjing, Chang, Yuzhou, Dheer, Aastha, Gao, Shan, Xu, Shengze, Ayasoufi, Katayoun, Al-kharboosh, Rawan, Xie, Manling, Johnson, Aaron J., Dong, Haidong, Quiñones-Hinojosa, Alfredo, Wu, Long-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104080/
https://www.ncbi.nlm.nih.gov/pubmed/37066234
http://dx.doi.org/10.1101/2023.04.05.535697

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