Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival

Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical roles in intestinal homeostasis and disease, few studies have...

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Detalles Bibliográficos
Autores principales: Danan, Charles H., Naughton, Kaitlyn E., Hayer, Katharina E., Vellappan, Sangeevan, McMillan, Emily A., Zhou, Yusen, Matsuda, Rina, Nettleford, Shaneice K., Katada, Kay, Parham, Louis R., Ma, Xianghui, Chowdhury, Afrah, Wilkins, Benjamin J., Shah, Premal, Weitzman, Matthew D., Hamilton, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104132/
https://www.ncbi.nlm.nih.gov/pubmed/37066277
http://dx.doi.org/10.1101/2023.04.06.535853

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