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Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls

For many cancers there are few well-established risk factors. Summary data from genome-wide association studies (GWAS) can be used in a Mendelian randomisation (MR) phenome-wide association study (PheWAS) to identify causal relationships. We performed a MR-PheWAS of breast, prostate, colorectal, lun...

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Detalles Bibliográficos
Autores principales: Went, Molly, Sud, Amit, Mills, Charlie, Hyde, Abi, Culliford, Richard, Law, Philip, Vijayakrishnan, Jayaram, Gockel, Ines, Maj, Carlo, Schumacher, Johannes, Palles, Claire, Kaiser, Martin, Houlston, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104236/
https://www.ncbi.nlm.nih.gov/pubmed/37066289
http://dx.doi.org/10.1101/2023.02.15.23285952